An estimation of genetic parameters of growth traits in juvenile turbot (<i>Scophthalmus maximus</i> L.) using parental molecular relatedness

HU Yulong; GUAN Jiantao; MA Yu; KONG Jie; WANG Weiji

doi:10.1007/s13131-015-0643-6

利用父母本微卫星标记估计大菱鲆(Scophthalmus maximus L.)幼鱼生长性状的遗传参数

doi: 10.1007/s13131-015-0643-6

1.
中国水产科学研究院黄海水产研究所, 青岛 266071
2.
中国水产科学研究院黄海水产研究所, 青岛 266071;中国海洋大学, 海洋生命学院, 青岛 266071

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- 收稿日期: 2014-09-23
- 修回日期: 2015-01-08

An estimation of genetic parameters of growth traits in juvenile turbot (Scophthalmus maximus L.) using parental molecular relatedness

1.
Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China
2.
Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao 266071, China;College of Marine Life, Ocean University of China, Qingdao 266003, China

摘要

摘要: 遗传参数估计在动物选择育种中占有重要地位。近年来,分子标记被广泛用于遗传评估,提高了评估的准确度。在仅一代系谱信息已知的情况下,为了提高遗传评估的准确度,构建包含39个家系的大菱鲆群体,收集了1890尾100日龄幼鱼的体重数据,借助线性混合模型(Linear Mixed Model),约束极大似然法(REML),分别利用根据亲本12对微卫星标记分型结果推导出的子代加性遗传相关系数(Parental Molecular Relatedness,PMR)和根据三代完整系谱估计的子代加性遗传相关系数(Pedigree Relatedness, PR)估计了子代体重性状的遗传力和育种值,利用交叉验证的方法比较了利用不同加性遗传相关系数预测遗传效应的准确度。结果显示,PMR和PR之间呈高度正相关(0.872),利用PMR和PR估计的遗传力分别为0.52±0.13和0.55±0.22,都属于高等遗传力,并且利用PMR和PR预测遗传效应的能力相同(0.81)。研究结果表明,当仅一代系谱已知时,PMR可以替代PR用于大菱鲆群体遗传参数估计。为了更好的比较PMR与PR,需要扩大微卫星标记数目及家系数目进一步研究。
- 大菱鲆(ScophthalmusmaximusL.) /
- 生长性状 /
- 加性遗传相关系数 /
- 遗传参数
Abstract: The estimation of genetic parameters has played an important role in animal selective breeding for growth traits. Recently studies show that molecular markers can be incorporated into genetic evaluations. In order to improve the performance of an incomplete pedigree (i.e, only parents are known) in the genetic evaluations, 12 microsatellite markers have been applied in the estimation of the genetic parameters for body weight in a farmed population (n=1 890) of juvenile turbot (Scophthalmus maximus L.). A new relatedness called parental molecular relatedness (PMR) is estimated based on results of genotyping of 48 parents (31 males, 17 females) with microsatellites markers. The feasibility of PMR in estimation of genetic parameters is verified by comparison with pedigree related (PR) which is obtained from a complete pedigree. The results demonstrate that a high correlation (0.872) between them is found. Heritabilities are estimated using the PMR (0.52±0.13) and PR (0.55±0.22) with the same animal model. A cross-validation shows that the predictive abilities of models using the PMR and the PR are identical (0.81). From that, a conclusion can be made that PMR and PR predicted genetic values equally well in a population of juvenile turbot. Therefore PMR can be applied as an alternative of the PR when only parents are known. However, for a better performance, more markers and more families should be included in a further study.
- parental molecular relatedness /
- pedigree relatedness /
- turbot /
- genetic parameters

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参考文献(29)

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文章访问数: 1455
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利用父母本微卫星标记估计大菱鲆(Scophthalmus maximus L.)幼鱼生长性状的遗传参数

doi: 10.1007/s13131-015-0643-6

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出版历程

An estimation of genetic parameters of growth traits in juvenile turbot (Scophthalmus maximus L.) using parental molecular relatedness

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出版历程

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