Comparison of short-term toxicity of 14 common phycotoxins (alone and in combination) to the survival of brine shrimp <i>Artemia salina</i>

Yuting Zhang; Shanshan Song; Bin Zhang; Yang Zhang; Miao Tian; Ziyi Wu; Huorong Chen; Guangmao Ding; Renyan Liu; Jingli Mu

doi:10.1007/s13131-022-2120-3

Volume 42 Issue 2

Feb. 2023

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Article Navigation > Acta Oceanologica Sinica > 2023 > 42(2): 134-141

Yuting Zhang, Shanshan Song, Bin Zhang, Yang Zhang, Miao Tian, Ziyi Wu, Huorong Chen, Guangmao Ding, Renyan Liu, Jingli Mu. Comparison of short-term toxicity of 14 common phycotoxins (alone and in combination) to the survival of brine shrimp Artemia salina[J]. Acta Oceanologica Sinica, 2023, 42(2): 134-141. doi: 10.1007/s13131-022-2120-3

Citation:

Yuting Zhang, Shanshan Song, Bin Zhang, Yang Zhang, Miao Tian, Ziyi Wu, Huorong Chen, Guangmao Ding, Renyan Liu, Jingli Mu. Comparison of short-term toxicity of 14 common phycotoxins (alone and in combination) to the survival of brine shrimp Artemia salina[J]. Acta Oceanologica Sinica, 2023, 42(2): 134-141. doi: 10.1007/s13131-022-2120-3

Citation:

Yuting Zhang, Shanshan Song, Bin Zhang, Yang Zhang, Miao Tian, Ziyi Wu, Huorong Chen, Guangmao Ding, Renyan Liu, Jingli Mu. Comparison of short-term toxicity of 14 common phycotoxins (alone and in combination) to the survival of brine shrimp Artemia salina[J]. Acta Oceanologica Sinica, 2023, 42(2): 134-141. doi: 10.1007/s13131-022-2120-3

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Comparison of short-term toxicity of 14 common phycotoxins (alone and in combination) to the survival of brine shrimp Artemia salina

doi: 10.1007/s13131-022-2120-3

Yuting Zhang^{1, 2},
Shanshan Song³,
Bin Zhang³,
Yang Zhang³,
Miao Tian^{1, 2},
Ziyi Wu¹,
Huorong Chen⁴,
Guangmao Ding⁴,
Renyan Liu^{3
,
,},
Jingli Mu^{1, 2
,
,}

1.
Institute of Oceanography, College of Geography and Oceanography, Minjiang University, Fuzhou 350108, China
2.
Fuzhou Institute of Oceanography, Fuzhou 350108, China
3.
Department of Marine Chemistry, National Marine Environmental Monitoring Center, Dalian 116023, China
4.
Fujian Marine Environment and Fishery Resource Monitoring Center, Fuzhou 350003, China

Funds: The National Natural Science Foundation of China under contract No. 41576120; the Special Fund Project for Marine and Fishery Protection and Development in Fujian Province, China under contract No. FZJZ-2021-1; the National Key R&D Program of China under contract No. 2017YFC1404803.

More Information

Corresponding author: E-mail: ryliu@nmemc.org.cn; jlmu@mju.edu.cn; jlmu@mju.edu.cn
Received Date: 2022-01-26
Accepted Date: 2022-09-19

Available Online: 2022-10-26

Publish Date: 2023-02-25

Abstract

Abstract

Toxic harmful algal blooms (HABs) can cause deleterious effects in marine organisms, threatening the stability of marine ecosystems. It is well known that different strains, natural populations and growth conditions of the same toxic algal species may lead to different amount of phycotoxin production and the ensuing toxicity. To fully assess the ecological risk of toxic HABs, it is of great importance to investigate the toxic effects of phycotoxins in marine organisms. In this study, the short-term toxicity of 14 common phycotoxins (alone and in combination) in the marine zooplankton Artemia salina was investigated. The 48 h LC₅₀ of the 14 phycotoxins varied from 0.019 3 µg/mL to 2.415 µg/mL. The most potent phycotoxin was azaspiracids-3 (AZA3; with a LC₅₀ of 0.019 3 µg/mL), followed by azaspiracids-2 (AZA2; 0.022 6 µg/mL), pectenotoxin-2 (PTX2; 0.046 0 µg/mL) and dinophysistoxin-1 (DTX1; 0.081 8 µg/mL). For the binary exposure, okadaic acid (OA) induced potential additive effects with DTX1, probably due to their similar structure (polyether fatty acid) and mode of action (attacking the serine/threonine phosphoprotein phosphatases). On the other hand, OA showed potential antagonistic effects with PTX2, which might be accounted for by their activation on the detoxification activity of cytochrome P450 activity. In addition, DTX1 induced potential synergetic effects with saxitoxin (STX), yessotoxin (YTX) or PTX2, suggesting the hazard potency of the mixtures of DTX1 and other phycotoxins (like STX, YTX and PTX2) with regard to the ecological risk. These results provide valuable toxicological data for assessing the impact of phycotoxins on marine planktonic species and highlight the potential ecological risk of toxic HABs in marine ecosystems.
- LC₅₀,
- harmful algal blooms,
- binary exposure,
- ecological risk

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References(53)

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